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Basic Science Review: Vascular Distensibility as a Predictive Tool in the Management of Small Asymptomatic Abdominal Aortic Aneurysms

Department of Vascular Surgery, Vascular Research Unit, Viborg Hospital, Denmark, a_l_hogh{at}yahoo.dk

Jes S. Lindholt, MD, PhD

Department of Vascular Surgery, Vascular Research Unit, Viborg Hospital, Denmark

Background: This study investigates whether baseline aortic wall distensibility serves as a supplemental bio-marker for AAA progression and need for later repair. Methods: In 1998, 61 males with a small asymptomatic AAAs had a baseline measurement of elasticity and stiffness, using an echo-tracking ultrasound system (Diamove). The cohort was followed till 2005 concerning Dmax, expansion rate, operations for AAA, hospitalisation do to cardiovascular disease and death. Results: During follow-up, 49% died, and 45.9% were hospitalised do to cardiovascular disease, compared to Dmax, Ep and b no significant associations were found. Elasticity correlated moderately to annual expansion rate and Dmax. Good correlation was found between annual expansion rate and Dmax. ROC-curve analysis showed that elasticity, stiffness and Dmax all tended to predict future need for AAA-repair. Conclusion: Baseline aortic wall distensibility may provide an additional parameter for AAA to optimize the indication and time for elective repair.

Key Words: AAA • distensibility • predictor of progression • follow-up studies

This version was published on August 1, 2009

Vascular and Endovascular Surgery, Vol. 43, No. 4, 333-338 (2009)
DOI: 10.1177/1538574409336019


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