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Midterm Follow-up After Pharmacomechanical Thrombolysis for Lower Extremity Deep Venous Thrombosis

Stony Brook University Medical Center, Surgery, Stony Brook, New York, antonios.gasparis{at}stonybrook.edu

Nicos Labropoulos, PhD

Stony Brook University Medical Center, Surgery, Stony Brook, New York

Apostolos K. Tassiopoulos, MD

Stony Brook University Medical Center, Surgery, Stony Brook, New York

Brett Phillips, MD

Stony Brook University Medical Center, Surgery, Stony Brook, New York

Jose Pagan, MD

Stony Brook University Medical Center, Surgery, Stony Brook, New York

Cheng Lo, MD

Stony Brook University Medical Center, Surgery, Stony Brook, New York

John Ricotta, MD

Stony Brook University Medical Center, Surgery, Stony Brook, New York

Objective: To provide follow-up in patients treated with pharmacomechanical thrombolysis (PhMT) for lower extremity deep venous thrombosis (DVT). Methods: Retrospective analysis of prospectively collected data. Patients underwent clinical evaluation, duplex ultrasound, venous clinical severity scoring, venous segmental disease scoring, and venous disability scoring. Results: Fourteen patients were available for evaluation. Median age was 40 years (19—58). Median follow-up was 24 months (13—69 months). Thirteen of 14 patients (93%) had a venous disability score < 1 and 13 of 14 patients (93%) had a venous clinical severity scoring < 5. In all but 1 patient the venous segmental disease scoring score was < 5. All iliac segments were patent, all but 3 patients had partial infrainguinal obstruction and 5 of 14 (36%) had reflux. Conclusions: Our data demonstrate that the good early clinical results after PhMT can be sustained on longer follow-up and may prevent the development of advanced postthrombotic syndrome.

Key Words: DVT • deep vein thrombosis • PhMT • pharmaco-mechanical thrombolysis • PTS • postthrombotic syndrome • VDS • venous disability score

This version was published on February 1, 2009

Vascular and Endovascular Surgery, Vol. 43, No. 1, 61-68 (2009)
DOI: 10.1177/1538574408323501


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