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Vascular and Endovascular Surgery
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Serum Creatinine Stabilization Following Renal Artery Stenting

Mark C. Bates, MD, FACC, FSCAI

Vascular Center of Excellence, mbates{at}camc.org, Robert C. Byrd Health Sciences Center, West Virginia University School of Medicine, Charleston Division, Charleston, West Virginia

John E. Campbell, MD

Robert C. Byrd Health Sciences Center, West Virginia University School of Medicine, Charleston Division, Charleston, West Virginia

Mike Broce

Outcomes Research Division

Philip S. Lavigne

Center for Clinical Sciences Research, Charleston Area Medical Center Research Institute

Mary A. Riley, DO

Robert C. Byrd Health Sciences Center, West Virginia University School of Medicine, Charleston Division, Charleston, West Virginia

The impact of renal artery stenting on renal function in a subgroup of consecutive de novo patients with atherosclerotic renal artery stenosis from the single operator, single center, retrospective renal stent trial is defined. Patients with inadequate preprocedure and/or follow-up renal function studies were excluded. Abnormal baseline serum creatinine (sCr) was defined as ≥1.5 mg/dL. Follow-up sCr was improved, unchanged, or worsened if the variance from baseline decreased by >20%, stayed within 20%, or increased >20%, respectively. For the total cohort (194 patients), renal function stabilized or improved in 72% of patients. Plotting 1/sCr demonstrated a decline in renal function before the procedure that stabilized following renal artery stenting. Bilateral renal artery stenting predicted normal follow-up sCr, and baseline sCr >2.1 mg/dL was associated with improvement in sCr long-term. In conclusion, renal artery stenting results in overall stabilization of renal function, and bilateral renal artery stenting seems to have added benefit.

Key Words: renal stent • angioplasty • outcomes • creatinine • renal artery • renal function

Vascular and Endovascular Surgery, Vol. 42, No. 1, 40-46 (2008)
DOI: 10.1177/1538574407308941


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