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Delayed-Onset Heparin-Induced Thrombocytopenia and Thrombosis After Intraoperative Heparin Anticoagulation

Four Case Reports

Department of Surgery, University of Texas Southwestern Medical Center, Dallas; Academic Department of Surgery, Greenville Hospital System, 701 Grove Road, Greenville, SC 29605 markjackson{at}ghs.org

William J. Neilson, MD

Michael Lary, MD

Peter Baay, MD

Amarillo Surgical Group, Amarillo

Kent Web, MD

Trinity Vascular Institute, Tyler, TX

G. Patrick Clagett, MD

Department of Surgery, University of Texas Southwestern Medical Center, Dallas

Delayed-onset heparin-induced thrombocytopenia (HIT) is a rare and only recently described condition. The authors report 4 cases of delayed-onset HIT, each of which presented with thrombotic complications 8–18 days after receiving heparin for coronary artery bypass grafting. Delayed-onset HIT should be suspected in any patient presenting with arterial or venous thromboembolism after heparin therapy, even 1 to 3 weeks after heparin exposure.

Vascular and Endovascular Surgery, Vol. 40, No. 1, 67-70 (2006)
DOI: 10.1177/153857440604000109


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