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Vascular and Endovascular Surgery
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Catheter-Directed Thrombolysis for Deep Venous Thrombosis

Zachary K. Baldwin, MD

Section of Vascular Surgery, Department of Surgery University of Chicago, Chicago, IL

Anthony J. Comerota, MD

Jobst Vascular Center, Toledo, OH

Lewis B. Schwartz, MD

Abbott Laboratories, Abbott Park, IL; Section of Vascular Surgery, Department of Surgery, University of Chicago MC 5028, 5841 S. Maryland Ave., Chicago, IL 60637 lschwart{at}surgery.bsd.uchicago.edu

Venous thromboembolism (VTE) represents a significant clinical problem, affecting patients of all age groups, nationalities, and socioeconomic strata. Despite its prevalence, the paradigms for care are largely centered around primary or secondary prophylaxis, with less emphasis on actual treatment of the thrombus. With the recent rapid development of advanced endovascular techniques, it is now feasible to dissolve many thrombi using catheter-directed thrombolysis (CDT), and favorable clinical experience has been reported in over 600 patients. If performed safely, the purported benefits of CDT for DVT include a decreased incidence of persistent phlebitic symptoms, improved quality of life and, possibly, a decreased incidence of recurrent thrombotic events.

Vascular and Endovascular Surgery, Vol. 38, No. 1, 1-9 (2004)
DOI: 10.1177/153857440403800101
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