This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Rayan, S. S. Articles by Pomposelli, F. B. Search for Related Content PubMed PubMed Citation Articles by Rayan, S. S. Articles by Pomposelli, F. B., Jr Pubmed/NCBI databases Medline Plus Health Information Aortic Aneurysm Diabetes Diabetes Complications Social Bookmarking                         What's this?

Is Diabetes a Risk Factor for Patients Undergoing Open Abdominal Aortic Aneurysm Repair?

Division of Vascular Surgery, Beth Israel Deaconess Medical Center, Boston, MA

Allen D. Hamdan, MD

Division of Vascular Surgery, Beth Israel Deaconess Medical Center, West Campus, 110 Francis St., Suite SB, Boston, MA 02215 ahamdan{at}caregroup.harvard.edu

David R. Campbell, MD

Cameron M. Akbari, MD

Shannon C. Hook, BS

John Skillman, MD

Frank W. LoGerfo, MD

Frank B. Pomposelli, Jr, MD

Division of Vascular Surgery, Beth Israel Deaconess Medical Center, Boston, MA

A number of studies have compared results after aortic procedures in diabetics vs nondiabetics but few have focused specifically on abdominal aortic aneurysm surgery. An analysis of prospective data was carried out in the Vascular Surgery Registry (Beth Israel Deaconess Medical Center, Boston, MA) and identified 421 patients (422 grafts) who underwent elective open repair of an abdominal aortic aneurysm between 1990 and 1999. The influence of diabetes mellitus on outcome was assessed by dividing the patients into two groups: 52 diabetic and 370 nondiabetic patients. Postoperative mortality was 1.7% overall (n =7) and proportionally higher in the diabetic population, although this did not reach statistical significance (3.8% vs 1.4%, p = 0. 19). However, cumulative survival at 1 year and 3 years was essentially identical for diabetic vs nondiabetic patients (91.0% vs 92.6% and 70.0% vs 73.5%, respectively) and did not diverge until 5 years after surgery (25.0% vs 50.9% respectively [p>0.05]). Overall, major complications occurred in 1 1 diabetics (21.2%) vs 58 nondiabetics (15.7%, p = 0.32). Specific complications that were increased in the diabetic population included pancreatitis (5.8% vs 1.1%, p = 0.01) and pneumonia (1 1.5% vs 3.2%, p = 0.006). Notably, overall cardiac morbidity was not higher in patients with diabetes mellitus (1.9% vs 4.3%, p = 0.41). Our data suggest that after elective open abdominal aortic aneurysm repair, patients with diabetes mellitus may have a higher rate of certain complications when compared to patients without diabetes mellitus. These differences however, do not preclude the expectation of excellent results of open abdominal aortic aneurysm repair in patients with diabetes mellitus.

Vascular and Endovascular Surgery, Vol. 36, No. 1, 33-40 (2002)
DOI: 10.1177/153857440203600107


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?