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Carotid Endarterectomy Based on Duplex Ultrasonography: A Safe Approach Associated with Long-term Stroke Prevention

Vascular and Surgery Associates, Sarasota, Florida

Dennis F. Bandyk

Division of Vascular Surgery, University of South Florida College of Medicine, Tampa, Florida

David P. Showalter

Vascular and Surgery Associates, Sarasota, Florida

Jonathan P. Yunis

Vascular and Surgery Associates, Sarasota, Florida

To evaluate the short-term and long-term safety of carotid endarterectomy (CEA) based on duplex ultrasound without confirmatory diagnostic arteriography.

A 4-year retrospective review of CEA based on duplex ultrasound alone (n = 653) or with confirmatory arteriography (n = 118) was performed in 244 women and 458 men whose ages ranged from 39 to 92 years (mean, 70 years). Practice patterns, perioperative morbidity, and stroke rate (life-table analysis) of a community-based and university- based vascular surgical practice were analyzed and compared.

Surgical intervention based on duplex ultrasound was judged possible in 85% of the patients (community, 93%; university, 55%). Indications for arteriography included: testing completed prior to surgical consultation (44%), nonfocal extracranial carotid stenosis (23%), nonhemispheric symptoms (13%), and prior stroke (9%). This approach was safe (with a combined operative mortality and neurologic morbidity of 1.8%), asso ciated with long-term stroke prevention (a 95% stroke-free survival at 4 years), and yielded results similar to CEA with arteriography (operative morbidity, 2.6%; 91% stroke- free survival). The incidence and nature of late neurologic deficits were similar after CEA with and without arteriography. Twenty-three (4%) of the patients who underwent CEA based on duplex ultrasound developed late neurologic symptoms including 9 contralat eral and 4 ipsilateral strokes; and 4 ipsilateral and 4 contralateral transient ischemic attacks (TIAs). Cardiac embolism from atrial fibrillation accounted for 6 strokes, lacunar infarct associated with hypertension (3 strokes), intracranial atherosclerosis (3 strokes), and contralateral internal carotid artery (ICA) occlusion (1 stroke). Forty patients (6.8%) died predominantly from cardiac events. After CEA with arteriography 6 (5%) of the patients died. Six late strokes (4 contralateral, and 2 ipsilateral hemisphere) occurred as a result of progressive, untreated ICA stenosis (n = 3), and lacunar infarct (n = 3). Overall, 11% of the patients underwent contralateral CEA for progressive ICA stenosis.

CEA, based on duplex scanning, is safe and applicable for the majority of patients undergoing surgical evaluation. Short-term and long-term outcomes were similar to outcomes in patients having CEA based on diagnostic arteriography.

Vascular and Endovascular Surgery, Vol. 34, No. 2, 125-136 (2000)
DOI: 10.1177/153857440003400204


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