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Limb Salvage With H.E.L.P (Heparin-induced Extracorporeal LDL Precipitation) In Peripheral Arterial Disease (PAD)

2nd Department of Surgery, Public & University Hospital, Graz

M. Walzl

Department of Neurology, University of Graz, Austria

B. Walzl

Department of Neurology, University of Graz, Austria

H. Lechner

Department of Neurology, University of Graz, Austria

H. Cesnik

2nd Department of Surgery, Public & University Hospital, Graz

Heparin-induced extracorporeal LDL precipitation (H.E.L.R) is based on the fact that lipoproteins and fibrinogen are precipitated at a pH value of 5.12 in the presence of heparin. The elimination of excess fibrinogen from the patient's blood leads to a marked improvement in microcirculation, followed by an increased oxygen supply to the tissue. This permits performance of limb-saving surgical procedures instead of mutilating amputations.

Ten patients suffering from far-advanced peripheral arterial disease (PAD) were submitted to 10 H.E.L.P. treatments each instead of undergoing amputations. Surgery could be limited to the removal of necrotic tissue only Wound-healing was uncompro mised in all the patients, and the H.E.L.P. treatment was free of side effects.

Vascular and Endovascular Surgery, Vol. 28, No. 6, 383-391 (1994)
DOI: 10.1177/153857449402800602


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