This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Yee, E. S. Search for Related Content PubMed Articles by Yee, E. S. Social Bookmarking                         What's this?

Accelerating HIV Infection with Cardiopulmonary Bypass—Case Reports

Department of Surgery, University of California, San Francisco, California

Five men patients and 1 woman patient who underwent either coronary artery bypass grafting (in 2) or valve replacement (in 3) or combined procedures (in 1) presented with severe HIV infection during the postoperative period. Four patients were NYHA Class III of IV with 3 patients in extremis requiring emergency procedures. All procedures were performed with cardiopulmonary bypass with mean time of 109 ± 48 minutes and aortic cross-clamp of 52 ± 49 minutes. Although the immediate postoperative courses seemed benign or uncomplicated, all presented with severe infections during the late postoperative period following their procedures (twenty-one to ninety days). The opportunistic infections were Pneumocystis carinii pneumonia (2), toxoplasmosis in the central nervous system and lung (1), cryptococcal meningitis (1), Staphylococcus aureus endocarditis (1), and viral encephalitis (1). Three died with two months of surgery.

These complicated postoperative infections have raised the question of the safety of cardiopulmonary bypass in HIV-infected patients. Rational recommendations regarding preoperative HIV antibody testing, operative indications, and postoperative surveillance are offered.

Vascular and Endovascular Surgery, Vol. 25, No. 9, 725-731 (1991)
DOI: 10.1177/153857449102500908


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?