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Vascular and Endovascular Surgery
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Angiographic Investigation of the Development of Collateral Circulation in the Rabbit

Shunro Endo

Toyama Medical and Pharmaceutical University, Toyama, Japan

Patricia J. Branson

Division of Neurological Surgery, University of California, San Diego, California

John F. Alksne

Division of Neurological Surgery, University of California, San Diego, California

The sequential changes seen on cerebral angiograms of rabbits after bilat eral common carotid artery ligation (carotid occlusion) are described. The basi lar artery increases in diameter and becomes tortuous within two weeks in the majority of animals in this study. The animals with the greatest increase in arterial lumen as determined by angiographic change had the fewest neurologic deficits. This model should be useful for studies on collateral flow.

Vascular and Endovascular Surgery, Vol. 23, No. 3, 201-207 (1989)
DOI: 10.1177/153857448902300307
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