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Vascular and Endovascular Surgery
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Response of Cutaneous Laser Velocimetry to a Temperature Change: Normal and Dysvascular Patients Compared

Gordon R. Neufeld

From the Department of Anesthesia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, Division of Anesthesia Research, Philadelphia Veterans Administration Medical Center, Philadelphia, Pennsylvania

Cheryl A. Reilly

Division of Anesthesia Research, Philadelphia Veterans Administration Medical Center, Philadelphia, Pennsylvania

Stephen R. Galante

Division of Anesthesia Research, Philadelphia Veterans Administration Medical Center, Philadelphia, Pennsylvania

Andrew B. Roberts

Division of Vascular Surgery, Medical College of Pennsylvania, Philadelphia, Pennsylvania

James E. Baumgardner

From the Department of Anesthesia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

David J. Graves

Department of Chemical Engineering, University of Pennsylvania, Philadelphia, Pennsylvania

John A. Quinn

Department of Chemical Engineering, University of Pennsylvania, Philadelphia, Pennsylvania

In previous studies of skin blood flow using a helium flux technique, we found a linear relationship between blood flow and skin temperature. In this paper we compared the helium flux method to laser Doppler velocimetry (LDV) over a range of temperatures in 5 normal healthy volunteers. In a separate normal group we measured the increase in LDV signal to a temperature change in both the volar aspect of the forearm and the dorsum of the foot. We then compared the LDV temperature response data from the normal subjects with data from a group of 20 patients with known peripheral vascular disease of the lower extremities and found a highly significant reduction in LDV output vs temperature in the patient groups. We concluded that the LDV temperature response data provide a convenient method for comparison of LDV data be tween patients and between sites on the same patient.

Vascular and Endovascular Surgery, Vol. 21, No. 5, 331-338 (1987)
DOI: 10.1177/153857448702100505
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