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Vascular and Endovascular Surgery
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Prevention of Early Recurrence of Aneurysmal Subarchnoid Haemorrhage by Tranexamic Acid: A Controlled Clinical Trial

Upendra Mohan Chowdhary

From the Department of Neurosurgery, College of Medicine and Medical Sciences, King Faisal University, Damman, Saudi Arabia

Kamaluddin Sayed

Assistant in Neurosurgery, St. Laurence's Hospital, Dublin, Ireland

A controlled clinical trial of Tranexamic Acid (TEA) was underaken to as sess its effectiveness in reducing early recurrence of haemorrhage in patients with aneurysmal subarchnoid haemorrhge (SAH). The series of control patients and patients having TEA which were consecutive. Of the 65 patients treated with TEA recurrence occurred in six (9%) and five patients died from recur rence of haemorrhage. Of the 64 patients in the control group, 17 (26%) pa tients had recurrent haemorrhage and eight patients died from it. Administra tion of tranexamic acid is found to have significantly reduced the early recur rence of haemorrhage.

Vascular and Endovascular Surgery, Vol. 20, No. 1, 8-13 (1986)
DOI: 10.1177/153857448602000102


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