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Prophylaxis Against Thromboembolism in Vascular Surgery

(A Randomised Clinical Trial)

Department of Cardiovascular Surgery, University Clinics, D-7800 Freiburg, Germany

G. Spillner

Department of Cardiovascular Surgery, University Clinics, D-7800 Freiburg, Germany

P. Schleinzer

Department of Cardiovascular Surgery, University Clinics, D-7800 Freiburg, Germany

H. Freidank

Department of Cardiovascular Surgery, University Clinics, D-7800 Freiburg, Germany

V. Schlosser

Department of Cardiovascular Surgery, University Clinics, D-7800 Freiburg, Germany

Thrombosis prophylaxis is indicated in vascular surgical patients for two general considerations: to prevent thromboembolism from the venous system and occlusion of reconstructed arterial vessels.

The purpose of this randomized, prospective study was to compare the effectiveness of low-dose heparin, heparin in combination with dihyder gotamine, and dextran-60 in the prevention of postoperative venous throm bosis and pulmonary embolism after vascular operations. In addition, any adverse effects of each medication on patency after arterial reconstruction was to be determined.

Vascular and Endovascular Surgery, Vol. 16, No. 4, 253-259 (1982)
DOI: 10.1177/153857448201600407


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